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PUBLICATION 04/2026EL2022-002/P2025-108Current insights on skin permeability data and QSPR modelling
Skin permeability is a critical factor in pharmaceuticals, cosmetics, and occupational safety. Experimental determination of skin permeability coefficients (Kp) is time-intensive and resource-demanding, highlighting the importance of…Learn more
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PUBLICATION 11/2024EL2022-002/P2024-077Percutaneous Absorption of Two Bisphenol A Analogues, BPAF and TGSA: Novel In Vitro Data from Human SkinBisphenol AF (BPAF) and 4,4'-Sulfonylbis[2-(prop-2-en-1-yl)phenol] (TGSA) are analogues of Bisphenol A (BPA). BPAF is commonly used in polymer synthesis, whereas TGSA finds application in thermal papers. BPAF is classified as toxic to reproduction 1B…
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PUBLICATION 02/2024EL2022-002/P2023-117Updating Skin Permeability Data: A Systematic Review of Recent ResearchCutaneous absorption parameters of xenobiotics are crucial in drug and cosmetic development, as well as in assessing environmental and occupational chemical risks. Despite the great variability in experimental condition designs due to…
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PUBLICATION 07/2024EL2020-003/P2023-192Human in vitro percutaneous absorption of bisphenol S: assessment of the skin reservoir and occlusion effectsBisphenol S (BPS) was introduced in many industrial and commercial applications as a presumed safer alternative to bisphenol A. However, concerns have been raised
surrounding skin absorption and potential persistence of BPS, and its related…Learn more