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PUBLICATION 09/2023EL2018-004/P2023-203Quantification of carbon nanotubes in biological matrices for toxicology purposesDespite numerous possible applications, the potential impact of Carbon Engineered Nanomaterials (CEN) on human health, particularly after exposure by inhalation, is still questioned. However, accurate quantification of CEN in the respiratory…
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PUBLICATION 05/2023EL2018-005/P2023-092Effect of multi-walled carbon nanotube exposure on wild type and p53+/- rat lungCarbon nanotubes (CNTs) are nanomaterials that can be inhaled by employees during production or handling. One CNT, the Mitsui-7 (MWNT-7), has been classified by the International Agency for Research on Cancer as possibly carcinogenic to humans…
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PUBLICATION 07/2023EL2018-005/P2023-078Needle-like, short and thin multi-walled carbon nanotubes: comparison of effects on wild type and p53+/- rat lungsLes nanotubes de carbone (NTC) sont des nanomat riaux qui pr sentent un risque professionnel d inhalation lors de leur production ou de leur manipulation. Le Centre International de Recherche sur le Cancer a class un NTC, le Mitsui-7 (MWNT-7), comme…
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PUBLICATION 05/2023EL2018-005/P2023-093Influence of the physicochemical properties of multi-walled carbon nanotubes on their toxicity in lung cellsMulti-walled carbon nanotubes (MWCNTs) are promising nanomaterials because of their various physicochemical properties. However, their production and handling can lead to their aerosolization. Then, they can be inhaled, reach the deep lung…
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PRESENTATION 05/2016NOETUDE/C2016-085In vitro cell transformation induced by amorphous silica nanoparticlesWorldwide production of silica nanoparticles is estimated to be one million tons per year. Unlike crystalline silica, silica nanoparticles which have an amorphous structure are so far not considered as carcinogen to humans by IARC. However…
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PRESENTATION 05/2016NOETUDE/C2016-087Epigenetic mechanisms involvement in in vitro cell transformation induced by micro- and nano-silica particlesEpigenetic mechanisms that are essential in normal cell growth have been found disrupted in several human diseases such as cancer. Epigenetic mechanisms include histone post-translational modifications, DNA methylation and non-coding…
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PRESENTATION 05/2016NOETUDE/C2016-089Epigenetic mechanisms involvement in in vitro cell transformation induced by micro- and nano-silica particlesEpigenetic mechanisms that are essential in normal cell growth have been found disrupted in several human diseases such as cancer. Epigenetic mechanisms include histone post-translational modifications, DNA methylation and non-coding…
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PUBLICATION 02/2025NOETUDE/P2024-099Influence of macrophages and neutrophilic granulocyte-like cells on crystalline silica-induced toxicity in human lung epithelial cellsIntroduction:
In many industrial activities, workers are exposed to particles that are either manufactured and used for their physicochemical properties or generated unintentionally during industrial processes. Since particles may get…Learn more
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PUBLICATION 09/2022NOETUDE/P2021-264A simple fluorescent cell-type specific labelling method for co-cultured cell flow cytometry analysisIntroduction:
Co-culture models have been extensively used for assessing the toxicity of fibres and particles. However, once cell lines are mixed in the same tissue culture well, it is difficult to evaluate differential cell toxicity without…Learn more
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STUDY 01/2016ET2016-005
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