Results of the search of scientific studies, publications and communications

N-vinyl-2-pyrrolidone (NVP) is mainly used as monomer in the production of polyvinylpyrrolidone or copolymers. Percutaneous absorption is an important source of exposure in the work environment. However, literature on this route of absorption…

The percutaneous route represents the second occupational exposure route for numerous industrial toxic substances. The word “Skin notation” appears whenever the contribution from this route to the total absorption by the body represents…

Ethyl to octyl esters of 2,4-dichlorophenoxy-acetic acids (2,4DAA), 2,4-dichlorophenoxy-propionic acids (2,4DPA) or 2,4-dichlorophenoxy-butyric acids (2,4DBA) are present in the most commonly used herbicides. Their use involves a significant risk…

Determining the intensity of the absorption flux of industrial toxic substances is necessary to define the risk related to exposure via the skin. Structure-activity relationships make it possible to estimate the absorption flux of numerous…

Outline of reasons and objectives
Measuring ex vivo percutaneous absorption of solid lipophilic toxic substances at ambient temperature, such as certain toxic substances already studied before (benzo[a]pyrene, pyrene, naphthalene, bisphenol…