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PUBLICATION 09/2023EL2018-004/P2023-203Quantification of carbon nanotubes in biological matrices for toxicology purposesDespite numerous possible applications, the potential impact of Carbon Engineered Nanomaterials (CEN) on human health, particularly after exposure by inhalation, is still questioned. However, accurate quantification of CEN in the respiratory…
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PRESENTATION 06/2016NOETUDE/C2016-103Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation studyDue to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PRESENTATION 07/2014EL2013-010/C2014-066DEVELOPMENT AND VALIDATION OF AN INHALATION SYSTEM SUITABLE FOR RODENT EXPOSURE TO NANOAEROSOLSDue to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological effects of these compounds have not been fully characterized yet. Because inhalation represents…
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PRESENTATION 02/2016NOETUDE/C2016-020Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study.Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PRESENTATION 03/2016EL2012-008/C2016-065Investigating how aromatic solvent exposure impacts acoustic reflexesSome volatile aromatic solvents have similar or opposite effects to anesthetics in the central nervous system. Like for anesthetics, the mechanisms of action involved are currently the subject of debate. The purpose of this in vivo study was…
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STUDY 01/2013EL2013-023Alterations in the amplitude of middle-ear acoustic reflex after inhalation of solvents. Physiological consequences for exposure to noise.
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STUDY 01/2014EL2014-011Alteration in the metabolism of styrene by co-exposure with 2-butanone (MEK)
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PRESENTATION 03/2016NOETUDE/C2016-058Extraction/derivation procedures for the determination of urinary acid metabolites of aromatic hydrocarbons by gas chromatography.Aromatic hydrocarbons (toluene, styrene, xylenes, ethylbenzene …) are among the most widely used chemicals in industry. Some of their urinary acid metabolites are classically used to assess the occupational exposure of workers to these solvents…
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PRESENTATION 02/2015NOETUDE/C2015-019Short- and long-term neurobehavioral toxicity of fluorene after a nose-only exposure during the lactating period (14 days) in F1 Wistar ratsAmong polycyclic aromatic hydrocarbons (PAHs), fluorene is a highly volatile compoundbeing one of the most abundant in air. Because significant fluorene concentrations have been measured in the breast milk of non-smoking women, the risk for…
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PRESENTATION 05/2015NOETUDE/C2015-059Short- and long-term neurobehavioral toxicity of fluorene after a nose-only exposure during the lactating period (14 days) in F1 Wistar ratsAmong polycyclic aromatic hydrocarbons (PAHs), fluorene is a highly volatile compoundbeing one of the most abundant in air. Because significant fluorene concentrations have been measured in the breast milk of non-smoking women, the risk for…
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