Results of the search of scientific studies, publications and communications

Pregnant Sprague-Dawley rats were administered deltamethrin, at doses of 0.1, 1, 5, or 10 mg/kg/day, or di-n-hexyl phthalate (DnHP) (250 mg/kg/day), by gavage, from gestation day (GD) 13 to 19. Maternal toxicity was observed at 10 mg/kg/day, as evidenced by transient…

N-ethyl-2-pyrrolidone (NEP) is an industrial solvent used in association or in replacement of N-methyl-2-pyrrolidone. Both are teratogenic in rats and are categorized as reproductive toxicants 1B by the European Commission. Nevertheless…

The solvent N-ethyl-2-pyrrolidone was evaluated in a 4-week repeated dose study in rats. NEP diluted in distilled water was administered by gavage to male and female Sprague-Dawley rats at doses of 0 (vehicle control), 5, 50, and 250 mg/kg/day for 28…

Pyrethroids are among the most commonly used classes of insecticides worldwide. Human exposure to pyrethroids is widespread, as evidenced by the presence of their metabolites in urine of adults, children, and pregnant and lactating women among…

Synthetic pyrethroids are present in numerous commercial insecticide formulations and have extensive worldwide indoor and outdoor applications, including agricultural, public, residential, and veterinary usages for pest control. Their…

Synthetic pyrethroids are used worldwide as insecticides. Their metabolites have been constantly measured in the urine of adults and children from the general population. There is increasing concern that they may induce sex-hormone disrupting…