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PUBLICATION 09/2023EL2018-004/P2023-203Quantification of carbon nanotubes in biological matrices for toxicology purposesDespite numerous possible applications, the potential impact of Carbon Engineered Nanomaterials (CEN) on human health, particularly after exposure by inhalation, is still questioned. However, accurate quantification of CEN in the respiratory…
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PRESENTATION 06/2016NOETUDE/C2016-103Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation studyDue to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PRESENTATION 02/2016NOETUDE/C2016-020Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study.Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PUBLICATION 05/2023EL2018-005/P2023-092Effect of multi-walled carbon nanotube exposure on wild type and p53+/- rat lungCarbon nanotubes (CNTs) are nanomaterials that can be inhaled by employees during production or handling. One CNT, the Mitsui-7 (MWNT-7), has been classified by the International Agency for Research on Cancer as possibly carcinogenic to humans…
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PUBLICATION 07/2023EL2018-005/P2023-078Needle-like, short and thin multi-walled carbon nanotubes: comparison of effects on wild type and p53+/- rat lungsLes nanotubes de carbone (NTC) sont des nanomat riaux qui pr sentent un risque professionnel d inhalation lors de leur production ou de leur manipulation. Le Centre International de Recherche sur le Cancer a class un NTC, le Mitsui-7 (MWNT-7), comme…
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PUBLICATION 08/2024EL2018-007/P2023-102Antifungal Climbazole alters androgenic pathways in mammalian cellsAmong antifungal agents used in pharmaceuticals (e.g., antimycotic foot care) and personal care products, the synthetic azole climbazole (CBZ; 1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one) acts on the fungus Malassezia. Despite…
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PUBLICATION 02/2025NOETUDE/P2024-099Influence of macrophages and neutrophilic granulocyte-like cells on crystalline silica-induced toxicity in human lung epithelial cellsIntroduction:
In many industrial activities, workers are exposed to particles that are either manufactured and used for their physicochemical properties or generated unintentionally during industrial processes. Since particles may get…Learn more
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PUBLICATION 09/2022NOETUDE/P2021-264A simple fluorescent cell-type specific labelling method for co-cultured cell flow cytometry analysisIntroduction:
Co-culture models have been extensively used for assessing the toxicity of fibres and particles. However, once cell lines are mixed in the same tissue culture well, it is difficult to evaluate differential cell toxicity without…Learn more