-
PUBLICATION 04/2024EL2018-004/P2023-162Analysis of Carbon nanotube levels in organic matter: an inter-laboratory comparison to determine best practiceCarbon nanotubes (CNTs) are increasingly being used in industrial applications, but their toxicological data in animals and humans are still rare. To understand the effects of CNTs, their quantification in tissues, especially lungs, is crucial…
Learn more
-
PUBLICATION 09/2023EL2018-004/P2023-203Quantification of carbon nanotubes in biological matrices for toxicology purposesDespite numerous possible applications, the potential impact of Carbon Engineered Nanomaterials (CEN) on human health, particularly after exposure by inhalation, is still questioned. However, accurate quantification of CEN in the respiratory…
Learn more
-
PRESENTATION 06/2016NOETUDE/C2016-103Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation studyDue to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
Learn more
-
PUBLICATION 07/2025EL2019-003/P2025-011Toluene, styrene and methyl-ethyl-ketone inhalation: Effects on the power of cortical oscillations in ratsIl est bien tabli que de nombreux solvants industriels peuvent provoquer une d pression du syst me nerveux central, caract ris e par de la somnolence, des tats d bri t , des baisses de concentration et de coordination, ce qui peut augmenter les risques…
Learn more
-
PRESENTATION 07/2014EL2013-010/C2014-066DEVELOPMENT AND VALIDATION OF AN INHALATION SYSTEM SUITABLE FOR RODENT EXPOSURE TO NANOAEROSOLSDue to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological effects of these compounds have not been fully characterized yet. Because inhalation represents…
Learn more
-
PRESENTATION 02/2016NOETUDE/C2016-020Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study.Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
Learn more
-
PRESENTATION 02/2016NOETUDE/C2016-025Development and validation of an inhalation system suitable for rodent exposure to carbon nanotubesDue to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed on laboratory…
Learn more
-
STUDY 01/2014EL2014-011Alteration in the metabolism of styrene by co-exposure with 2-butanone (MEK)
Learn more
-
PRESENTATION 03/2016NOETUDE/C2016-058Extraction/derivation procedures for the determination of urinary acid metabolites of aromatic hydrocarbons by gas chromatography.Aromatic hydrocarbons (toluene, styrene, xylenes, ethylbenzene …) are among the most widely used chemicals in industry. Some of their urinary acid metabolites are classically used to assess the occupational exposure of workers to these solvents…
Learn more
-
PUBLICATION 07/2025EL2018-002/P2025-025Tricresyl phosphate gestational exposure induced endocrine and metabolic disruptionsOrganophosphate flame retardants (OPFRs), including tricresyl phosphate (TCP), are incorporated into a wide variety of polymers to give them fire resistance. They are therefore present in numerous industrial and consumer products such as electrical…
Learn more