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PRESENTATION 10/2015NOETUDE/C2015-079Brain inflammation and Blood Brain Barrier disruption after sub-acute inhalation exposure to titanium dioxide nanoparticle aerosol in aging ratsNotwithstanding potential neurotoxicity of Titanium dioxide nanoparticles (TiO2 NPs), the toxicokinetics and consequences on blood brain barrier (BBB) functions remain poorly characterized. We previously described the biodistribution…
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STUDY 01/2016EL2016-016
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PRESENTATION 12/2014NOETUDE/C2014-120Biokinetic comparison after single I.V. administration or chronic aerosol inhalation of TiO2 nanoparticles : impact on blood-brain barrierNotwithstanding the translocation of reported TiO2 nanoparticles (NPs) through biological barriers, the bio-distribution of TiO2NPs to the CNS and impact on the functions of the BBB remain poorly characterized. We report such evidence.
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