Results of the search of scientific studies, publications and communications

Notwithstanding potential neurotoxicity of Titanium dioxide nanoparticles (TiO2 NPs), the toxicokinetics and consequences on blood brain barrier (BBB) functions remain poorly characterized. We previously described the biodistribution…

The increasing industrial use of nanoparticles (NPs) has raised concern about their impact on human health. Since aging and exposure to environmental factors are linked to the risk for developing pathologies, we address the question of TiO2 NPs…

The aim of this conference, organised by INRS and supported by the Partnership for European Research in Occupational Health and Safety (PEROSH), was to review knowledge of allergies, invalidating and very often under-estimated pathologies, in…

Occupational allergies are among the most frequent of occupational diseases, because numerous sensitizing substances and organisms are present in the working world. Often underestimated, such pathologies can become very disabling and can…

Notwithstanding the translocation of reported TiO2 nanoparticles (NPs) through biological barriers, the bio-distribution of TiO2NPs to the CNS and impact on the functions of the BBB remain poorly characterized. We report such evidence.
Adult…

The mechanisms of action involved in the neurotoxicity of solvents are poorly understood. Studies have suggested that the effects of some solvents might be due to the formation of reactive oxygen species (ROS). This study assesses hydroxyl radical…

The aim of this conference, organised by INRS and supporte by the Partnership for European Research in Occupational Health and Safety (PEROSH), was to review knowledge of allergies, invalidating and very often under-estimated pathologies, in…

Exposure to 1,2-diethylbenzene (1,2-DEB) has been shown to induce peripheral neuropathy in rats. 1,2-diacetylbenzene (1,2-DAB), a g-diketone-like compound, is thought to be the active metabolite responsible for the neurotoxicity observed. Moreover…