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STUDY 01/2010B.4/1.087Studies of the in vitro genotoxic effects of nanostructured silica particles produced by different manufacturing processesOutline of reasons and objectives
Nanoparticles of synthetic amorphous silica (SAS) are produced in large quantities worldwide (1 million metric tons/year) and they have numerous industrial uses. SASs can be broken down into two main types depending…Learn more
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PRESENTATION 05/2016NOETUDE/C2016-085In vitro cell transformation induced by amorphous silica nanoparticlesWorldwide production of silica nanoparticles is estimated to be one million tons per year. Unlike crystalline silica, silica nanoparticles which have an amorphous structure are so far not considered as carcinogen to humans by IARC. However…
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PRESENTATION 05/2016NOETUDE/C2016-087Epigenetic mechanisms involvement in in vitro cell transformation induced by micro- and nano-silica particlesEpigenetic mechanisms that are essential in normal cell growth have been found disrupted in several human diseases such as cancer. Epigenetic mechanisms include histone post-translational modifications, DNA methylation and non-coding…
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PRESENTATION 05/2016NOETUDE/C2016-089Epigenetic mechanisms involvement in in vitro cell transformation induced by micro- and nano-silica particlesEpigenetic mechanisms that are essential in normal cell growth have been found disrupted in several human diseases such as cancer. Epigenetic mechanisms include histone post-translational modifications, DNA methylation and non-coding…
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PUBLICATION 10/1999B.5/2.040/3566/NS178Constructing, translating and validating a questionnaire. The example of EUROQUESTQuestionnaires are information gathering tools that are often irreplaceable in research. Multidimensional scales are best adapted to investigating diseases or disorders involving several components (such as depression or deterioration…
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