Results of the search of scientific studies, publications and communications

Fluorene is one of the most abundant polycyclic aromatic hydrocarbons in air and may contribute to the neurobehavioral alterations induced by the environmental exposure of humans to PAHs. Since no data are available on fluorene neurotoxicity…

Toluene is widely used in industry, with an annual consumption close to 20 million tons. Occupational exposure to toluene is commonly assessed using hippuric acid and ortho-cresol despite their low specificity and poor sensitivity. Levels…

1. Toluene (TOL) is a CMR solvent which is metabolized via the glutathione pathway, producing benzylmercapturic, o-, m- and p-toluylmercapturic acids (MAs). These metabolites could be useful as biomarkers of TOL exposure.
2. The aims of this work were…

In a first study, rats were given diisooctyl phthalate (DIOP, CAS 27554-26-3) at 0, 0.1, 0.5, and 1 g/kg/day, by gavage, on gestation days 6 through 20 (GD). There was a significant increase in resorptions at 1 g/kg/day and a reduction in fetal weights at 0.5 and 1 g/kg…

At workplaces, noise that is low-frequency rich is omnipresent and it can be associated with solvents, such as carbon disulphide, for example. That solvent, which is used in manufacturing cellulose and more particularly viscose, is known to give…