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Results of the search of scientific studies, publications and communications

Author(s) : COSNIER F.
36 results
  • Neurobehavioral toxicity of a repeated exposure (14 days) to the airborne Polycyclic Aromatic Hydrocarbon fluorene in adult Wistar male rats. NOETUDE/P2013-078 | 2013
    Fluorene is one of the most abundant polycyclic aromatic hydrocarbons in air and may contribute to the neurobehavioral alterations induced by the environmental exposure of humans to PAHs. Since no data are available on fluorene neurotoxicity…
  • Optimization of mineralization methods of TiO2 nanoparticles: Determination of titanium levels in rat organ tissues NOETUDE/C2015-051 | 2015
    Titanium dioxide nanoparticles (TiO2 NPs) are among the highest produced nanoparticles in the world today and are increasingly being incorporated into a wide range of construction and domestic products. Production on such a massive scale raises…
  • Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study NOETUDE/C2016-103 | 2016
    Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
  • Membrane fluidity does not explain how solvents act on the middle-ear reflex EL2013-023/P2015-175 | 2016
    Some volatile aromatic solvents have similar or opposite effects to anesthetics in the central nervous system. Like for anesthetics, the mechanisms of action involved are currently the subject of debate. This paper presents an in vivo study…
  • DEVELOPMENT AND VALIDATION OF AN INHALATION SYSTEM SUITABLE FOR RODENT EXPOSURE TO NANOAEROSOLS EL2013-010/C2014-066 | 2014
    Due to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological effects of these compounds have not been fully characterized yet. Because inhalation represents…
  • Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study. NOETUDE/C2016-020 | 2016
    Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
  • Investigating how aromatic solvent exposure impacts acoustic reflexes EL2012-008/C2016-065 | 2016
    Some volatile aromatic solvents have similar or opposite effects to anesthetics in the central nervous system. Like for anesthetics, the mechanisms of action involved are currently the subject of debate. The purpose of this in vivo study was…
  • Design and characterization of an inhalation system to expose rodents to nanoaerosols EL2013-010/P2015-167 | 2016
    The number of workers potentially exposed to nanoparticles (NPs) in industrial processes is constantly increasing, even though the toxicological effects of these compounds have not yet been fully characterized. The hazards associated with…
  • Alterations in the amplitude of middle-ear acoustic reflex after inhalation of solvents. Physiological consequences for exposure to noise. EL2013-023 | 2013
  • Impact of co-exposure on toluene biomarkers in rats B.4/2.160/P2013-077 | 2014
    Toluene is widely used in industry, with an annual consumption close to 20 million tons. Occupational exposure to toluene is commonly assessed using hippuric acid and ortho-cresol despite their low specificity and poor sensitivity. Levels…
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