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PUBLICATION 04/2024EL2018-004/P2023-162Analysis of Carbon nanotube levels in organic matter: an inter-laboratory comparison to determine best practiceCarbon nanotubes (CNTs) are increasingly being used in industrial applications, but their toxicological data in animals and humans are still rare. To understand the effects of CNTs, their quantification in tissues, especially lungs, is crucial…
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PUBLICATION 09/2023EL2018-004/P2023-203Quantification of carbon nanotubes in biological matrices for toxicology purposesDespite numerous possible applications, the potential impact of Carbon Engineered Nanomaterials (CEN) on human health, particularly after exposure by inhalation, is still questioned. However, accurate quantification of CEN in the respiratory…
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PRESENTATION 04/2015NOETUDE/C2015-051Optimization of mineralization methods of TiO2 nanoparticles: Determination of titanium levels in rat organ tissuesTitanium dioxide nanoparticles (TiO2 NPs) are among the highest produced nanoparticles in the world today and are increasingly being incorporated into a wide range of construction and domestic products. Production on such a massive scale raises…
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PRESENTATION 06/2016NOETUDE/C2016-103Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation studyDue to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PUBLICATION 07/2025EL2019-003/P2025-011Toluene, styrene and methyl-ethyl-ketone inhalation: Effects on the power of cortical oscillations in ratsIl est bien tabli que de nombreux solvants industriels peuvent provoquer une d pression du syst me nerveux central, caract ris e par de la somnolence, des tats d bri t , des baisses de concentration et de coordination, ce qui peut augmenter les risques…
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PRESENTATION 07/2014EL2013-010/C2014-066DEVELOPMENT AND VALIDATION OF AN INHALATION SYSTEM SUITABLE FOR RODENT EXPOSURE TO NANOAEROSOLSDue to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological effects of these compounds have not been fully characterized yet. Because inhalation represents…
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PRESENTATION 02/2016NOETUDE/C2016-020Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study.Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PRESENTATION 03/2016EL2012-008/C2016-065Investigating how aromatic solvent exposure impacts acoustic reflexesSome volatile aromatic solvents have similar or opposite effects to anesthetics in the central nervous system. Like for anesthetics, the mechanisms of action involved are currently the subject of debate. The purpose of this in vivo study was…
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STUDY 01/2013EL2013-023Alterations in the amplitude of middle-ear acoustic reflex after inhalation of solvents. Physiological consequences for exposure to noise.
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PRESENTATION 02/2016EL2013-010/C2016-018Titaninium dioxide-induced gene expression profile in rat lung, a sub-acute inhalation study.Due to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological properties of these compounds are not fully known. Inhalation represents the main route of occupational…
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