Results of the search of scientific studies, publications and communications

Titanium dioxide nanoparticles (TiO2 NPs) are among the highest produced nanoparticles in the world today and are increasingly being incorporated into a wide range of construction and domestic products. Production on such a massive scale raises…

Due to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological effects of these compounds have not been fully characterized yet. Because inhalation represents…

Notwithstanding potential neurotoxicity of Titanium dioxide nanoparticles (TiO2 NPs), the toxicokinetics and consequences on blood brain barrier (BBB) functions remain poorly characterized. We previously described the biodistribution…

The increasing industrial use of nanoparticles (NPs) has raised concern about their impact on human health. Since aging and exposure to environmental factors are linked to the risk for developing pathologies, we address the question of TiO2 NPs…

Occupational noise can damage workers' hearing, and the phenomenon is even more dangerous when noise is associated with an ototoxic solvent. Aromatic solvents are known to provoke chemical-induced hearing loss, but little is known about the…

Due to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological properties of these compounds are not fully known. Since these particles can be aerosolised, the…

In order to draw appropriate conclusions about the possible adverse biological effects of titanium dioxide nanoparticles (TiO2-NPs), the so-called “dose-effect” relationship must be explored. This requires proper quantification of titanium…

Notwithstanding the translocation of reported TiO2 nanoparticles (NPs) through biological barriers, the bio-distribution of TiO2NPs to the CNS and impact on the functions of the BBB remain poorly characterized. We report such evidence.
Adult…

The mechanisms of action involved in the neurotoxicity of solvents are poorly understood. Studies have suggested that the effects of some solvents might be due to the formation of reactive oxygen species (ROS). This study assesses hydroxyl radical…

Notwithstanding the reported advances in the translocation of titanium dioxide nanoparticles (TiO2 NPs) through biological barriers, the biodistribution of TiO2 NPs to the central nervous system as well as the functional consequences of…