Results of the search of scientific studies, publications and communications

N-vinyl-2-pyrrolidone (NVP) is mainly used as monomer in the production of polyvinylpyrrolidone or copolymers. Percutaneous absorption is an important source of exposure in the work environment. However, literature on this route of absorption…

Ethyl to octyl esters of 2,4-dichlorophenoxy-acetic acids (2,4DAA), 2,4-dichlorophenoxy-propionic acids (2,4DPA) or 2,4-dichlorophenoxy-butyric acids (2,4DBA) are present in the most commonly used herbicides. Their use involves a significant risk…

For testing skin absorption of chemical substances, OECD Test Guideline 428 (OECD, 2004)1 provides some recommendations as to how substances should be prepared:
“The test substance preparation (e.g., neat, diluted or formulated material containing…

Outline of reasons and objectives
Measuring ex vivo percutaneous absorption of solid lipophilic toxic substances at ambient temperature, such as certain toxic substances already studied before (benzo[a]pyrene, pyrene, naphthalene, bisphenol…