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PRESENTATION 06/2016NOETUDE/C2016-103Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation studyDue to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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PRESENTATION 02/2016NOETUDE/C2016-020Pulmonary toxicity and genotoxicity of carbon nanotubes in rats, a subacute inhalation study.Due to their physical and chemical properties, carbon nanotubes (CNTs) are among the most promising nanomaterials in terms of industrial use. In order to assess their toxicological properties, inhalation experiments performed in laboratory…
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STUDY 01/2010B.4/1.087Studies of the in vitro genotoxic effects of nanostructured silica particles produced by different manufacturing processesOutline of reasons and objectives
Nanoparticles of synthetic amorphous silica (SAS) are produced in large quantities worldwide (1 million metric tons/year) and they have numerous industrial uses. SASs can be broken down into two main types depending…Learn more
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STUDY 01/2013EL2013-010Study of the effect of agglomeration on the respiratory toxicological properties and the toxicokinetics of inhaled nanoparticles of titanium dioxide in ratsDue to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological properties of these compounds are not fully known. Since these particles can be aerosolised, the…
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PUBLICATION 05/2023EL2018-005/P2023-093Influence of the physicochemical properties of multi-walled carbon nanotubes on their toxicity in lung cellsMulti-walled carbon nanotubes (MWCNTs) are promising nanomaterials because of their various physicochemical properties. However, their production and handling can lead to their aerosolization. Then, they can be inhaled, reach the deep lung…
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PRESENTATION 05/2016NOETUDE/C2016-085In vitro cell transformation induced by amorphous silica nanoparticlesWorldwide production of silica nanoparticles is estimated to be one million tons per year. Unlike crystalline silica, silica nanoparticles which have an amorphous structure are so far not considered as carcinogen to humans by IARC. However…
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PRESENTATION 05/2016NOETUDE/C2016-087Epigenetic mechanisms involvement in in vitro cell transformation induced by micro- and nano-silica particlesEpigenetic mechanisms that are essential in normal cell growth have been found disrupted in several human diseases such as cancer. Epigenetic mechanisms include histone post-translational modifications, DNA methylation and non-coding…
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PRESENTATION 05/2016NOETUDE/C2016-089Epigenetic mechanisms involvement in in vitro cell transformation induced by micro- and nano-silica particlesEpigenetic mechanisms that are essential in normal cell growth have been found disrupted in several human diseases such as cancer. Epigenetic mechanisms include histone post-translational modifications, DNA methylation and non-coding…
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PUBLICATION 02/2025NOETUDE/P2024-099Influence of macrophages and neutrophilic granulocyte-like cells on crystalline silica-induced toxicity in human lung epithelial cellsIntroduction:
In many industrial activities, workers are exposed to particles that are either manufactured and used for their physicochemical properties or generated unintentionally during industrial processes. Since particles may get…Learn more