Results of the search of scientific studies, publications and communications

Outline of reasons and objectives
Following the expert appraisal work published in 2009 by the French Agency for Environmental and Occupational Health & Safety (Agence Francaise de Securite Sanitaire de l’Environnement et du Travail) on asbestos…

Skin permeability is a critical factor in pharmaceuticals, cosmetics, and occupational safety. Experimental determination of skin permeability coefficients (Kp) is time-intensive and resource-demanding, highlighting the importance of…

Bisphenol AF (BPAF) and 4,4'-Sulfonylbis[2-(prop-2-en-1-yl)phenol] (TGSA) are analogues of Bisphenol A (BPA). BPAF is commonly used in polymer synthesis, whereas TGSA finds application in thermal papers. BPAF is classified as toxic to reproduction 1B…

Cutaneous absorption parameters of xenobiotics are crucial in drug and cosmetic development, as well as in assessing environmental and occupational chemical risks. Despite the great variability in experimental condition designs due to…

Bisphenol S (BPS) was introduced in many industrial and commercial applications as a presumed safer alternative to bisphenol A. However, concerns have been raised
surrounding skin absorption and potential persistence of BPS, and its related…

Le bisph nol E (BPE) et le bisph nol B (BPB) apparaissent comme des alternatives au bisph nol A (BPA), bien que les informations sur leur toxicit et sur l'exposition humaine restent limit es. Bien qu'ils ne soient pas officiellement class s comme tels, ces…

Outline of reasons and objectives
Recent work has highlighted new activities such as carbon densification and repairing facilities covered with pitch-based coatings, and during which occupational exposure to Polycyclic Aromatic Hydrocarbons…

Low-pressure carburizing is a heat treatment process used to harden surface steel by enriching the metal with carbon atoms coming from pyrolysis of hydrocarbons. Unfortunately, at the same time, other species, considered to be proved to be carcinogenic…

Polycyclic Aromatic Hyrocarbons (PAHs) are chemical compounds that are sometimes highly toxic, or indeed that are considered by some to be proved carcinogens. A variety of sectors of activity cause PAH emissions: incineration, pyrolysis, diesel…

Climbazole is an antifungal substance used as an active ingredient or antimicrobial preservative in pharmaceuticals and personal care products. It is classified by the EU as an acute toxicant (Category 4), and ECHA has recently confirmed its…