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Results of the search of scientific studies, publications and communications
Author(s) : BURGART M.
4 results
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Toluene is widely used in industry, with an annual consumption close to 20 million tons. Occupational exposure to toluene is commonly assessed using hippuric acid and ortho-cresol despite their low specificity and poor sensitivity. Levels…
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Biomarkers of toluene exposure in rats: mercapturic acids vs. traditional indicators (urinary hippuric acid and o-cresol and blood toluene) B.4/2.160/P2012-173 | 20131. Toluene (TOL) is a CMR solvent which is metabolized via the glutathione pathway, producing benzylmercapturic, o-, m- and p-toluylmercapturic acids (MAs). These metabolites could be useful as biomarkers of TOL exposure.
2. The aims of this work were… -
Extraction/derivation procedures for the determination of urinary acid metabolites of aromatic hydrocarbons by gas chromatography. NOETUDE/C2016-058 | 2016Aromatic hydrocarbons (toluene, styrene, xylenes, ethylbenzene …) are among the most widely used chemicals in industry. Some of their urinary acid metabolites are classically used to assess the occupational exposure of workers to these solvents…
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Adverse effects of diisooctyl phthalate on the male rat reproductive development following prenatal exposure B.4/2.161/P2013-090 | 2013In a first study, rats were given diisooctyl phthalate (DIOP, CAS 27554-26-3) at 0, 0.1, 0.5, and 1 g/kg/day, by gavage, on gestation days 6 through 20 (GD). There was a significant increase in resorptions at 1 g/kg/day and a reduction in fetal weights at 0.5 and 1 g/kg…
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