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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/publication.html?refINRS=NOETUDE%2FP2014-182
Rationale: Although asbestos is a well-known lung carcinogen, the association between pleural plaques and lung cancer remains controversial. Objective: The present study was designed to examine this association among asbestos-exposed workers…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/presentation.html?refINRS=ET2015-003%2FC2016-113
The ExproNano project aims at providing a methodology for assessing exposure to nanoparticules (manufactured or not) that combines both an aerosol measurement component (via real time aerosol measurements and aerosol sampling) and a work task…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/presentation.html?refINRS=NOETUDE%2FC2015-103
In 2014, French ministries were alerted by local authorities following the identification of naturally occurring actinolite in aggregates used in road paving. In the environment, actinolite, as well as others amphiboles, are present in both…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/presentation.html?refINRS=EL2013-010%2FC2014-066
Due to the growing use of nanoparticles in industrial processes, the number of workers potentially exposed is increasing while the toxicological effects of these compounds have not been fully characterized yet. Because inhalation represents…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/publication.html?refINRS=EL2013-010%2FP2015-167
The number of workers potentially exposed to nanoparticles (NPs) in industrial processes is constantly increasing, even though the toxicological effects of these compounds have not yet been fully characterized. The hazards associated with…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/publication.html?refINRS=B.4%2F2.160%2FP2013-077
Toluene is widely used in industry, with an annual consumption close to 20 million tons. Occupational exposure to toluene is commonly assessed using hippuric acid and ortho-cresol despite their low specificity and poor sensitivity. Levels…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/publication.html?refINRS=B.4%2F2.160%2FP2012-173
1. Toluene (TOL) is a CMR solvent which is metabolized via the glutathione pathway, producing benzylmercapturic, o-, m- and p-toluylmercapturic acids (MAs). These metabolites could be useful as biomarkers of TOL exposure.
2. The aims of this work were…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/presentation.html?refINRS=NOETUDE%2FC2016-058
Aromatic hydrocarbons (toluene, styrene, xylenes, ethylbenzene …) are among the most widely used chemicals in industry. Some of their urinary acid metabolites are classically used to assess the occupational exposure of workers to these solvents…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/publication.html?refINRS=EL2012-008%2FP2014-032
Both noise and styrene are damaging for the organ of Corti. Since the solvent is often present with noise, this co-exposure must be considered as a typical framework for workers risk assessment. If styrene impairs the cochlea by a long process, it…
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https://en.inrs.fr/home/our-activities/studies-and-research/studies-publications-communications/doc/study.html?refINRS=EL2014-017
For a long time, evaluation of exposure to chemical compounds was limited to measuring merely the volatile fraction of the compounds and thus to exposure by inhalation. However, the use of semi-volatile products and other particular substances…