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List of studies
Discipline(s) : Toxicologie expérimentale
14 results
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Percutaneous absorption of industrial esters: structure-activity relationship between absorption flux and substitution of the aromatic-type acid group EL2015-008 | 2015Determining the intensity of the absorption flux of industrial toxic substances is necessary to define the risk related to exposure via the skin. Structure-activity relationships make it possible to estimate the absorption flux of numerous…
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Development of an in vitro co-culture model for evaluating the sensitising potential of industrial substances. EL2014-013 | 2014Every year, new chemical substances appear in the industrial field. It is becoming essential to identify such potentially sensitizing substances as early as possible. Developing tests for identifying the sensitising power of industrial products…
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Ex vivo percutaneous absorption of solid lipophilic toxic substances: use of an artificial sebum type vehicle B.4/2.165 | 2011Outline of reasons and objectives
Measuring ex vivo percutaneous absorption of solid lipophilic toxic substances at ambient temperature, such as certain toxic substances already studied before (benzo[a]pyrene, pyrene, naphthalene, bisphenol… -
Compared harmfulness of impulse noise and of steady-state noise having the same acoustic energy during co-exposure to styrene EL2012-008 | 2012Outline of reasons and objectives
In its recommendations on protecting the hearing of employees exposed to noise of occupational origin, the Noise Directive 2003/10/EC does not take into account the nature of the noise, i.e. whether it is steady-state… -
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Studies of the in vitro genotoxic effects of nanostructured silica particles produced by different manufacturing processes B.4/1.087 | 2010Outline of reasons and objectives
Nanoparticles of synthetic amorphous silica (SAS) are produced in large quantities worldwide (1 million metric tons/year) and they have numerous industrial uses. SASs can be broken down into two main types depending… -
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